Application fields of clean sheds and clean rooms

Clean booths and clean rooms are two different levels of clean space solutions, widely used in fields with strict requirements for air quality, microbial control, and particle contamination. The following is a comparison of the core application fields and feature analysis of the two:
I. Application Fields and Characteristics of Clean Booths
Core application scenarios
Electronic manufacturing industry
Scenarios: semiconductor chip packaging, precision electronic component assembly, SMT surface mount technology, LCD/OLED panel production, etc.
Requirement: Control fine dust particles (such as particles ≥0.5μm) to prevent static electricity and contamination from causing short circuits or performance failures of components.
Level: Generally, it can reach ISO 5 (10,000 level) to ISO 7 (1,000 level) in terms of cleanliness. In some local areas, it can be upgraded to a higher level through laminar flow hoods.
Food and drug production
Scenarios: Sterile drug repackaging, health product weighing/packaging, food additive preparation, high-cleanliness raw material processing, etc.
Requirements: Control microorganisms (such as bacteria and molds) and dust particles to comply with GMP (Good Manufacturing Practice for Pharmaceuticals) requirements.
Grade: Mostly ISO 7 (10,000 grade) to ISO 8 (100,000 grade), and in some areas, sterilization equipment is required to achieve higher cleanliness standards.
Laboratories and research scenarios
Scenarios: biological laboratories, chemical analysis rooms, cell culture rooms, small animal experiment areas, etc.
Requirements: Isolate the source of pollution, prevent cross-contamination in experiments, and protect the accuracy of samples or experimental results.
Level: Adjusted according to the type of experiment, it is usually ISO 6 (1000 level) to ISO 8 level, and local high-cleanliness areas can be flexibly built.
Temporary or transitional cleaning requirements
Scenarios: temporary clean areas during factory production line renovations, precision equipment displays at exhibitions, medical emergency testing points, etc.
Features: Modular design, quick disassembly, and assembly, lower cost than fixed cleanrooms, suitable for short-term or mobile scenarios.
The core advantages of the clean booth
High flexibility: The size can be adjusted according to demand, and equipment such as laminar flow hoods and FFU (fan filter units) can be installed to upgrade the cleanliness level.
Low cost: No major construction is required, and the installation period is short (usually 1-3 days), making it suitable for scenarios with limited budgets or limited space.
Convenient maintenance: Performance can be maintained by simply replacing local filters (such as primary and high-efficiency filters), and the maintenance cost is low.
Ii. Application Fields and Characteristics of Cleanrooms
Core application scenarios
Pharmaceutical and medical device manufacturing
Scenarios: injection production (such as large-volume parenteral, freeze-dried powder injections), sterile medical device assembly (such as syringes, and implantable devices), vaccine production workshops, etc.
Requirements: Strictly control microorganisms, dust particles, and cross-contamination, and obtain certifications from regulatory authorities such as FDA and NMPA.
Level: Usually ISO level 5 (Class 100) to ISO level 7. The aseptic filling area needs to reach ISO level 5 (static) or higher (such as isolator technology).
The semiconductor and microelectronics industry
Scenarios: chip lithography, wafer manufacturing, semiconductor packaging and testing, hard disk head production, etc.
Requirements: Control nanoscale particles (such as particles ≥0.1μm), maintain a constant temperature (22±0.5℃) and humidity (45±5% RH), and prevent static electricity from damaging precision components.
Level: Mostly ISO level 4 (10) to ISO level 5, and some lithography machine areas need to reach ISO Level 3 (1) ultra-clean standard.
Aerospace and precision machinery
Scenarios: assembly of aviation instruments, processing of precision bearings, coating of optical lenses, integration of avionics, etc.
Requirements: To prevent particle contamination from affecting mechanical accuracy or optical performance, and to control temperature and humidity to prevent material deformation.
Level: Usually ISO 6 (1000 level) to ISO 7 level. Local laminar flow equipment can be configured for key processes.
Medical surgery and life sciences
Scenarios: Laminar flow operating rooms (such as orthopedics and cardiac surgery), sterile transplant wards, gene therapy laboratories, biosafety laboratories (BSL-2/3), etc.
Requirements: Control the spread of bacteria through unidirectional airflow, maintain positive pressure to prevent external contamination, and comply with the specifications for clean operating departments in hospitals (GB 50333).
The operating room is usually of ISO level 6 (1000) to ISO level 5 (100), and the core surgical area needs to reach ISO level 5.
The core advantages of cleanrooms
High stability: Full-room-level clean control is achieved through building structures (such as color steel plate partition walls, and epoxy resin floors) and air conditioning systems (such as combined air handling units), making it suitable for long-term and high-demand scenarios.
Multi-functional integration: It can integrate complex functions such as temperature and humidity control, pressure difference monitoring, fire protection systems, and gas supply, meeting the strict requirements of production processes.
Strong compliance: Conforms to international/national standards (such as ISO 14644, GMP, FDA), and is suitable for production or experimental environments that require certification.
Iii. Summary of Key Differences
Dimensional clean shed clean room
The cleanliness level is usually from ISO 5 to ISO 8 and can be upgraded locally to cover ISO 3 to ISO 8. The entire room is of high cleanliness
Structural features: Modular frame + transparent curtain/hardboard, non-fixed fixed building structure (color steel plate/stainless steel wall panel), strong sealing performance
The installation period is 1 to 3 days, and it can be quickly disassembled and assembled within several weeks to several months. It needs to be coordinated with civil engineering and pipeline works.
Low cost (about 1/3 to 1/2 of that of a cleanroom) High (involving comprehensive costs such as decoration, air conditioning systems, and fire protection)
Applicable scenarios: temporary clean areas, local high-demand areas, long-term production/experiments in budget-limited scenarios, high compliance requirements, and large-scale Spaces
Iv. Selection Suggestions
Give priority to clean booths: If the demand is for short-term use, partial cleanliness upgrade, a limited budget, or flexible space adjustments, such as temporary production lines in electronics factories or temporary clean benches in laboratories.
Priority should be given to cleanrooms: If long-term stable operation, high cleanliness throughout the room (such as ISO level 5 or below), or if regulatory certification is involved (such as in pharmaceutical production), such as semiconductor wafer factories and sterile preparation workshops.
The two can be used in combination. For example, a clean booth can be set up in the clean room as a micro-environment enhancement area (such as building an ISO 5-level precision assembly station with a clean booth in an ISO 7-level clean room) to optimize cost and performance.