What are the basic requirements of the GMP cosmetics workshop?

GMP cosmetics workshop refers to the production workshop that meets a series of cosmetic production specifications, which is suitable for the establishment and management of cosmetic production workshops and is an important link to ensure the quality and safety of cosmetics. Next, Zhongjing Purification will introduce the basic requirements of a cosmetic GMP workshop based on experience in constructing purification projects for cosmetic units.
First of all, the site of the cosmetics GMP workshop should meet the relevant standards. The total area of the production, filling, and packaging room shall not be less than 100 square meters, and the area per person shall not be less than 4 square meters. The net height of the workshop shall not be less than 2.5m, the height of the waterproof layer shall not be less than 1.5m, and the buffer belt shall be set up in front of the production workshop. The floor of the production workshop should be smooth, acid-resistant, alkali-resistant, wear-resistant, non-slip, dust-proof, non-irritating, impervious, and easy to clean and disinfect. Walls and ceilings should be made of light-colored heat-resistant, moisture-proof, corrosion-resistant, anti-virus materials, and materials that do not easily produce dust and breed bacteria, such as colored steel plates. The floor of the work area to be cleaned shall be sloped to avoid water accumulation and shall have a floor drain with a cover at the lowest point.
Secondly, cosmetic GMP workshops must have suitable facilities and equipment. The workshop should be kept clean, tidy, and well-ventilated, and equipped with necessary environmental control equipment. The production area should be equipped with changing rooms, a wardrobe, a shoe rack, and other changing facilities, and set up running water, hand washing, and cleaning facilities. The production workshop with a visiting corridor, should be separated from the production area by a glass wall to prevent man-made pollution. In addition, the equipment in the workshop should be regularly maintained and calibrated to ensure its normal operation and accuracy.
Then, the cosmetics GMP workshop needs a proper material and goods flow system. This includes properly classifying and labeling raw materials, packaging materials, and finished products to avoid confusion and cross-contamination. At the same time, to ensure the orderly flow of goods by the specified process. The access to the production workshop should be spacious and barrier-free. In the workshop, a special area should be set up for the storage and processing of raw materials and finished products, a storage room for semi-finished products, a filling room, a clean container storage room, and a buffer zone to ensure transportation and health and safety protection.
At the same time, cosmetic GMP workshops also require effective environmental monitoring and control. The total number of bacteria in the air of the production workshop shall not exceed 1000 /m³. Air, water quality and surface microorganisms should be regularly monitored to ensure that the workshop environment meets the standard requirements. In addition, appropriate source control measures should be put in place in the workshop, such as avoiding residues and cross-contamination.
In addition, cosmetic GMP workshops have strict requirements for process control and recording. Process parameters and operating procedures should be clearly defined, standardized, and trained to ensure each worker understands and complies with them. Each process should have clear and detailed records to trace product quality and safety. The workshop also requires a reasonable verification and verification plan for the production and process to ensure the reliability and consistency of product quality.