What factors affect the disinfection effect of the VHP pass box?

The disinfection effect of VHP transfer Windows is influenced by multiple factors, mainly including the following aspects:
Hydrogen peroxide concentration: Hydrogen peroxide concentration is a key factor affecting the disinfection effect. Generally speaking, both excessively high and low concentrations are not conducive to achieving the best disinfection effect. The concentration is too low to effectively kill microorganisms. If the concentration is too high, it may not only cause waste but also have adverse effects such as corrosion on the disinfected items, and at the same time increase the impact of decomposition products on the environment. Generally, the hydrogen peroxide concentration used in VHP transfer Windows is around 30% to 50%, and the specific concentration needs to be optimized based on the characteristics of the equipment and the objects to be disinfected.
Disinfection time: The disinfection time is also crucial to the disinfection effect. If the disinfection time is too short, hydrogen peroxide cannot fully contact and exert its effect on microorganisms, making it difficult to achieve the purpose of thorough disinfection. However, if the disinfection time is too long, it may cause damage to the material of the disinfected items, and at the same time, it will increase costs and reduce work efficiency. Different microorganisms have varying degrees of tolerance to hydrogen peroxide. Therefore, for different disinfection objects, it is necessary to determine the appropriate disinfection time through experiments, which generally ranges from a few minutes to tens of minutes.
Temperature and humidity
Temperature: Temperature affects the vaporization rate of hydrogen peroxide and the metabolic activities of microorganisms. Appropriately raising the temperature can accelerate the vaporization of hydrogen peroxide, enabling it to exert its disinfection effect more quickly. However, excessively high temperatures may cause hydrogen peroxide to decompose too rapidly, reducing its effective concentration, and may also cause damage to the disinfected items. Generally speaking, it is more appropriate to control the disinfection temperature of the VHP transfer window at 20℃ - 40℃.
Humidity: The influence of humidity on the disinfection effect is rather complex. On the one hand, appropriate humidity helps hydrogen peroxide form a uniform water film on the surface of microorganisms, increasing the contact area between it and the microorganisms, thereby enhancing the disinfection effect. On the other hand, excessive humidity will dilute the concentration of hydrogen peroxide, affecting its bactericidal ability and may also cause the surface of the disinfected items to become damp. Generally, the relative humidity during the disinfection of VHP transfer Windows should be maintained at around 40% to 60%.
Air circulation and circulation: Good air circulation and circulation are crucial for the disinfection effect of VHP transfer Windows. Through the air circulation system, vaporized hydrogen peroxide can be evenly distributed within the transfer window, ensuring that items in every corner can be thoroughly disinfected. Meanwhile, air circulation can also promptly discharge the waste gas and condensate water produced during the disinfection process, preventing them from adversely affecting the disinfection effect. If the air circulation is poor, it may lead to local accumulation or uneven distribution of hydrogen peroxide gas, affecting the overall disinfection effect.
The nature and surface condition of the disinfected items
Material of items: Items made of different materials have different tolerances and adsorbilities to hydrogen peroxide. Some materials such as metal and glass are relatively stable to hydrogen peroxide, are not easily corroded, and have a good disinfection effect. However, some materials such as plastics and rubbers may adsorb hydrogen peroxide, affecting the disinfection effect and even causing deformation and aging. Therefore, for items made of different materials, appropriate disinfection parameters need to be selected based on their characteristics.
Surface cleanliness: The cleanliness of the surface of an item directly affects the disinfection effect. If there is dirt, grease, bloodstains, and other organic substances on the surface of the items, it will hinder the contact between hydrogen peroxide and microorganisms, reducing the disinfection effect. Therefore, before disinfection, the items must be thoroughly cleaned to remove surface contaminants.
The shape and structure of items: The complexity of the shape and structure of items can also affect the disinfection effect. For items with regular shapes and simple structures, hydrogen peroxide gas can easily cover their surfaces evenly and has a better disinfection effect. For items with complex shapes, pores, or crevices, hydrogen peroxide gas may not be able to fully penetrate the interior, resulting in incomplete disinfection. In this case, it may be necessary to appropriately extend the disinfection time or adopt other auxiliary disinfection methods.